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Hyperpigmentation is a prevalent skincare concern that can be caused by various factors including acne. It can take a toll on your self confidence and be tricky to address this skin concern with regular skincare products alone. In this blog post, we’ll explore the causes of hyperpigmentation and delve deeper into targeted treatments that can reduce its appearance to gain a radiant and even toned complexion.

What types of hyperpigmentation are there?

There are different types of hyperpigmentation that are caused by a range of factors that contribute to the development of dark spots or uneven complexions. This includes environmental factors, medical conditions or trauma to the skin.


Melasma is a type of hyperpigmentation that appears most frequently in areas like the stomach and face and occurs due to hormonal changes in the body. This includes pregnancy but also when you are stressed for long periods of time. If you have a darker complexion or a woman between the ages of 20 – 40 years old, you are more likely to develop melasma.

Post inflammatory hyperpigmentation

Post inflammatory hyperpigmentation occurs when injury, inflammation or trauma happens on the skin. Your skin combats this by producing extra melanin to try and protect itself which can result in dark spots or patches. Some examples of inflammatory circumstances that can take place involve conditions such as eczema, acne and psoriasis but it can also involve burns, cuts or infections on the skin.


Sunspots appear in areas like the hands or face or any part of the body most exposed to the sun. To protect your skin from the sun’s damage, your body creates a brown pigment called melanin. When you are over exposed to the sun’s UV rays without SPF or low factor SPF, your body produces more melanin to protect your body sufficiently. This can often result in dark or brown spots or splotches on the body.

Close up shot of the lower half of a woman's face - showing hyperpigmentation on her face caused by acne
Female shoulder close up with a scar - causes hyperpigmentation and darker, uneven skin tone

What treatments are available?

To treat hyperpigmentation, there are many targeted treatments that can reduce the visibility of dark spots or patches on the skin.

Alpha hydroxy acids (AHAs)

Alpha hydroxy acids or AHAs are a group of acids that naturally form in various foods. It is found in skincare to exfoliate the skin more effectively than products such as scrubs. Some of the most common types of AHAs are glycolic acid and lactic acid and these work to improve skin texture whilst also reducing hyperpigmentation. It works by promoting cell turnover and production to create new cells that are evenly pigmented.

Skin boosters

Skin boosters revitalise the complexion of the skin and improve the overall complexion. They are an injectable treatment that formulated using the key ingredient hyaluronic acid. When injected, they improve issues such as dehydrated skin, firmness, improve collagen production and reduce signs of ageing. It also targets hyperpigmentation due to this, as skin cell turnover is stimulated.

At Refine Pharma, we have an exciting range of skin boosters available to treat your various skin concerns including hyperpigmentation. Explore below.

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Retinol is form of vitamin A that can be found in various skincare products such creams or serums but strong concentrations can also be bought over the counter or prescribed by a healthcare professional. Retinol works similarly to AHAs by exfoliating the skin and increasing cell production. However, one of the key differences is that retinol stimulates a larger level of collagen production. This can target issues like hyperpigmentation as well creating firmer and radiant looking and feeling skin.


Polynucleotides are an injectable treatment used to rejuvenate the skin. They work in a similar manner to skin boosters but work within the cells to provide more than hydration. They provide medicine and foods for the skin cells which promotes cell turnover and production. This forms healthier skin cells that have the ability to produce an even amount of melanin and pigment. Want to learn more about polynucleotides? Check out this blog post.

Here at Refine Pharma, we have a range of polynucleotide products available to treat hyperpigmentation. This includes big name brands such as Nucleofill. Check out our entire range below.

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Cream and gel textures on a beige/pink background - using retinols in skincare products can treat hyperpigmentation
Profhilo H+L on a white table and pink gradient background
Close up of a pipette from a serum bottle - retinol in different forms such as serums can aid with hyperpigmentation
Nucleofill Medium on a white table and turquoise background